After his sister was devoured by a dragon and all their supplies were lost in a failed dungeon raid, Lyos and his party are completely broke and have resorted to eating the monsters they hunt, but are still determined to save her before she gets digested. They then meet a dwarf who introduces them to the world of Dungeon Meshi: delicious cuisine made from ingredients such as the flesh of giant bats, walking mushrooms and even screaming mandrake.